Fig. 5: DSF increases the CD4 + CD25+ Foxp3+ regulatory T cell subset in grafts. | Communications Biology

Fig. 5: DSF increases the CD4 + CD25+ Foxp3+ regulatory T cell subset in grafts.

From: Disulfiram treatment suppresses antibody-producing reactions by inhibiting macrophage activation and B cell pyrimidine metabolism

Fig. 5

a Flow cytometry plot of CD25+Foxp3+ cells in the CD3 + CD4+ leukocyte gate of the graft-infiltrated cells. b Data of FCM profiles of the percentage of CD25+ Foxp3+ cells in CD4+ cells (left) and absolute cell number CD4 + CD25+ Foxp3+ cells (right). n = 7 biologically independent mice. c Data of FCM profiles of the percentage of CD4 + T cells in leukocytes (left) and absolute cell number CD4 + T cells (right). n = 7 biologically independent mice. d Immunofluorescent staining of CD4+ (green) and Foxp3+ (red) cells in the graft. Significance was calculated using two-tailed unpaired Student’s t test. *P < 0.05, **P < 0.01.

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