Fig. 2: ADAR2 KO decreased body weight and liver weight in male obese mice. | Communications Biology

Fig. 2: ADAR2 KO decreased body weight and liver weight in male obese mice.

From: Deficiency of ADAR2 ameliorates metabolic-associated fatty liver disease via AMPK signaling pathways in obese mice

Fig. 2

Physiological parameters in mice from the age of 5–17 weeks (n = 18 mice/group) (a, male; b, female) body weight (BW, g); (c, male; d, female) weights of liver, epididymal adipose, BAT, epicardial adipose, and kidney derived from WT and ADAR2 KO mice fed with ND or HFD are shown (n = 18) All data are expressed as mean ± SEM. Tukey’s multiple comparison test after the two-way ANOVA was conducted for (a–d). *ND-WT group versus HFD-WT group or ND-KO group versus HFD-KO group; **p < 0.01, ***p < 0.001, ****p < 0.0001; #HFD-WT group versus HFD-KO group; ##p < 0.01, ###p < 0.001, ####p < 0.0001; n.s, not significant.

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