Fig. 5: Effect of the MSUS paradigm on beta diversity metrics of fecal microbiota across life.
From: Transgenerational effects of early life stress on the fecal microbiota in mice
Comparison of MSUS versus control mice is displayed. Visualization as principal correspondence analysis of (a−e) binary (microbial composition) and (f−j) weighted Jaccard index (microbial structure). a, f pnd22, (b, g) pnd30, (c, h) week08, (d, i) week15, and (e, j) week30 are depicted. Small symbols display aggregated microbiota per litter (pnd22) or cage (pnd30, week08, week15, and week30), large symbols display centroids, ellipses indicate 95% of confidence intervals. k Heatmap of R2 for comparison between MSUS and control at different time points. Significance was calculated using PERMANOVA including FDR correction. Number of animals per group are stated in Supplementary Table 4. Comparisons of different dispersions between MSUS and controls at different time points are listed in Supplementary Table 3. pnd: postnatal day; ns: not significant; **p < 0.01.
