Fig. 1: Interfaces in CytoSIP. CKs are colored in yellow, and CKRs are colored in light gray.
From: CytoSIP: an annotated structural atlas for interactions involving cytokines or cytokine receptors
Heavy chain and Light chain of antibody are colored in magenta and lavender accordingly. The interfaces show sticks and surface on the structure. This coloring scheme applies to all protein–protein interface figures unless otherwise stated. a Category 2a interaction interface in CK-CKR complex (IL2-IL2R complex, PDB ID: 1Z92); b Category 2b Epitope in CK-antibody complex (CXC motif chemokine 2 complexed with its antibody, PDB ID:5OB5); c Category 2c Targeted surface in CK-drug complex (BMP2 complexed with L-tartaric acid, PDB ID: 4UI2).
