Fig. 5: BA indices (percentages or ratios) of sulfated BAs and gut microbial transformed BAs.
From: Comparative profiling of serum, urine, and feces bile acids in humans, rats, and mice
a–c The ratio of sulfated BAs to unsulfated BAs in humans, rats, and mice. d The ratio of sulfated BAs to unsulfated BAs in BA group among humans, rats, and mice. e, f The residual T-conj-BAs and G-conj-BAs among humans, rats, and mice. g–o The BA ratios of microbial transformed BAs. The ratio of unconj-BAs to conj-BAs (g), DCA group to CA group (h), LCA group to CDCA group (i), 3-ketoCA to CA (j), 7-ketoCA to CA (k), 12-ketoCDCA to CA (l), 7-ketoLCA to CDCA (m), UCA to CA (n) and isoLCA to CA (o) among humans, rats, and mice. Human (n = 50), rat (n = 14), and mice (n = 14). G-conj-BAs glycine-conjugated BAs, T-conj-BAs taurine-conjugated BAs, unconj-BAs unconjugated BAs, tri-OH BA trihydroxy BA, di-OH BAs dihydroxy BA, mono-OH BA monohydroxy BA. CA group: the sum of CA, TCA, and GCA. DCA group: the sum of DCA, TDCA, and GDCA. CDCA group: the sum of CDCA, TCDCA, and GCDCA. LCA group: LCA, TLCA and GLCA. * indicates p < 0.05, ** indicates p < 0.01. Error bars depict the standard error of the mean (SEM).
