Fig. 6: Acetylome analysis of A. fumigatus ∆sirE strain.
From: Sirtuin E deacetylase is required for full virulence of Aspergillus fumigatus
A Venn diagram of proteins found in the total proteome, enriched fraction, and lysine-acetylated proteins of WT and ∆sirE strains. B Distribution of the number of acetylated sites (Kac) in the proteome. C Heat map of peptides containing Kac-sites showing changes in abundance when WT and ∆sirE are compared (FDR adjusted t-test < 0.05). Kac-peptide intensities were z-score normalized, and Euclidean distance hierarchical clustering was applied to rows and columns. D GO enrichment analysis of the 40 proteins with differentially abundant Kac sites was performed using FungiDB and visualized on the SRPlot website.
