Fig. 6: Mass univariate relationships between deviation and symptom scores.

a Only two of these deviation-symptom relationships were significant. Significant pFDR values are shown for the relationships between PC2 and deviations within the VAChT- and mGluR5-enriched networks (A; anterior view, L; left view, R; right view, S; superior view). SMA; supplementary motor area, STG; superior temporal gyrus. b The same relationships are shown in the brain plots, with Z values averaged across the significant clusters and correlated with PC2 symptom scores. The loadings for PC2 are shown again here for context. Of note, whilst the diagnostic groups are reported in different colours within the scatter plots, this is purely for visualisation purposes and these analyses were run transdiagnostically across all patient groups.