Fig. 3: Two-color STORM images and quantitative analysis reveals spatial relationship between nuclear DNA and RNAPII or PCNA in T cells at quiescent and activated states. | Communications Biology

Fig. 3: Two-color STORM images and quantitative analysis reveals spatial relationship between nuclear DNA and RNAPII or PCNA in T cells at quiescent and activated states.

From: Super-resolution imaging of T lymphocyte activation reveals chromatin decondensation and disrupted nuclear envelope

Fig. 3

a, c Representative two-color STORM images of genomic DNA and RNAPII or PCNA before and after stimulation. Scale bars: 2 µm and 1 µm in the original and magnified images, respectively. b, d The average size of RNAPII or PCNA nanoclusters and degree of colocalization between nuclear DNA and RNAPII or PCNA (n = 63 and 58 cells, respectively for RNAPII; n = 74 and 60 cells, respectively, for PCNA).

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