Fig. 4: GWAS analysis for heifer puberty and gene expression profile for PLAG1 and HMGA2.

a. Genome wide association with 48.8 million SNP for heifer puberty. Odd chromosomes are coloured blue, even chromosomes in red. The significance threshold on the y-axis is 8.3 (e.g. -log10(5 × 10–8). Only SNPs with significance > 3 (P-value < 0.0001) are shown. b. Gene expression (Fragments Per Kilobase of transcript per Million mapped reads) in foetal and adult tissues for PLAG1 and c. HMGA2, data from the bovine gene expression atlas (Fang et al.31).