Fig. 1: Schematic of experimental setup for ECED transport.
From: Electrokinetic convection-enhanced delivery for infusion into the brain from a hydrogel reservoir
a Ex vivo brain placed over a microscope slide under the stereoscope. b Configuration of hydrogel placement, capillary insertion, and schematic representation of the expected fluorophore infusion inside the brain. c Experimental conditions of diffusion-only control and ECED, with a representative example from each, created by merging a brightfield image with the fluorescent image. d In vivo subject placed on the stereotaxic device, showing a single craniotomy where the hydrogel and capillary were placed. e Detailed configuration of hydrogel and capillary placement in coronal view, with a schematic representation of the expected fluorophore infusion inside the brain. f Experimental conditions of diffusion-only control and ECED, with a representative example for each.
