Fig. 2: Higher locus coeruleus (LC) activation in older adults.

Higher locus coeruleus (LC) activation in older adults for a (1) emotional salience: loss > gain feedback (red-yellow), b (2) task-related salience: reversal > no reversal feedback (green-yellow), c (3) memory performance: remembered > not remembered (purple-blue) and d (4) emotional memory performance: remembered before loss feedback > not remembered before loss feedback (blue-green). Significant activations (a–d) shown in each colour with a threshold of p < 0.005 (threshold of p < 0.003 outlined in white) are in sagittal (first row), coronal (middle row), and axial (bottom row) views, within the LC meta mask (grey) created by ref. ¹⁰².