Fig. 7: Quality checks of structural and functional LC imaging data.
From: Functional locus coeruleus imaging to investigate an ageing noradrenergic system
a The distribution of inter-subject distances for the left and right LC centroid voxels of the aggregated LC meta mask102 and the MNI-transformed LC segmentations for individual subjects are shown in violin plots. Boxplots within the violin plot show error bars with 95% confidence interval. In-plane distance is calculated separately for the left and right LC, slice by slice, and averaged across slices to obtain a value per subject and left or right LC segmentation (right: M±SD=0.81 ± 0.19, IQR = 0.28; left: M ± SD=0.81 ± 0.27, IQR = 0.21). b Histograms of in-plane distances between single-subject landmarks and landmarks defined on the MNI template. The dashed red line indicates the typical width of the LC (2.5 mm22 below which deviations should fall24, in fact median deviations all fell below 1 mm.
