Table 1 Unique non-synonymous Single Nucleotide Polymorphisms detected in early H58 S. Typhi

From: The origins of haplotype 58 (H58) Salmonella enterica serovar Typhi

Gene ID

SNP Position in CT18

Gene

Reference nucleotide

4.3.1 nucleotide

Ancestral codon

Derived codon

Ancestral amino acid

Derived amino acid

Functional Category

Product

STY0376

387595

 

C

T

ACC

ATC

T

I

Central/intermediary metabolism

putative rtn protein; diguanylate cyclase/ phosphodiesterase domain-containing protein

STY0452

461438

yajI

G

A

CGT

TGT

R

C

Membrane/surface structures

putative lipoprotein

STY0522

529155

kefA/aefA

A

G

AAA

GAA

K

E

Membrane/surface structures

integral membrane protein AefA

STY0698

693560

rlpB

C

T

ATG

ATA

M

I

Central/intermediary metabolism

rare lipoprotein B precursor

STY1458

1408039

 

C

T

CAG

TAG

Q

*

 

putative lipoprotein

STY1703

1629304

ssaP

G

A

GCG

GTG

A

V

Pathogenicity/adaptation/chaperones

putative type III secretion protein

STY2371

2202853

 

C

T

CGT

TGT

R

C

Membrane/surface structures

putative nucleoside permease

STY2513

2348633

glpA

G

A

GGC

AGC

G

S

Central/intermediary metabolism

anaerobic glycerol-3-phosphate dehydrogenase subunit A

STY2553

2388057

nuoG

G

A

ACT

ATT

T

I

Information transfer

NADH dehydrogenase I chain G

STY2564

2401233

yfbT

G

A

CGC

TGC

R

C

Central/intermediary metabolism

putative phosphatase

STY3518

3360344

nanE2

T

C

ATA

GTA

I

V

Pseudogenes

conserved hypothetical protein (pseudogene)

STY3795

3659647

Ydey

C

T

GGG

GAG

G

E

Membrane/surface structures

Putative ABC transporter protein, AI-2 transport system permease

STY4405

4273783

metH

C

A

CGT

AGT

R

S

Central/intermediary metabolism

B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase

STY4451

4321540

 

A

G

AAG

AGG

K

R

 

single-strand DNA-binding protein

STY4890

4754034

 

C

T

TGG

TAG

W

*

 

probable carbon starvation protein

STY4890

4754035

 

A

G

TGG

CGG

W

R

 

probable carbon starvation protein

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