Fig. 4: Catalytic sites of LcsG. | Communications Biology

Fig. 4: Catalytic sites of LcsG.

From: Characterization of a methyltransferase for iterative N-methylation at the leucinostatin termini in Purpureocillium lilacinum

Fig. 4

a SAH binding sites of OxaC (PDB code: 5w7p, marked in pink), LepI (PDB code: 6ix7, marked in blue), and LcsG (marked in golden). b Modified LeuA binding sites of LcsG (Maestro, Schrödinger, LLC). c Comparison of wild-type LcsG and mutated LcsG-mediated methylation. The yield of the product was quantified by comparison with the peak area of the product catalyzed by LcsG (100%). All the data are represented as the means of n = 3 biologically independent samples and the error bars show the standard deviations.

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