Fig. 6: Differences in the microbiome of female and male mice after testosterone treatment.
From: The effect of testosterone on the gut microbiome in mice

On day 21, treated female (a, day 21) and male (b, day 21) mice (n = 6) exhibited significantly different bacterial communities compared to controls based on weighted UniFrac (p = 0.007, p = 0.027, respectively). c Pairwise analysis of the weighted distance changes between paired samples (males and females together) before and after treatment showed that the microbiota of control mice changed significantly more (p = 0.02). d PCoA of weighted UniFrac distance matrices of considering sex and treatment for each treatment group on day 21. Volcano plots of significantly different metabolites from the comparison between (e) male control T21 and male testosterone T21 (f) female control T21 and female testosterone T21 (n = 4).