Fig. 7: Timeline of the emergence of estX-carrying bacteria from 1979 to 2023.
From: The global distribution of the macrolide esterase EstX from the alpha/beta hydrolase superfamily
Green arrows indicate the first appearance of estX-carrying bacteria on each continent. Black arrows indicate the first discovery of estX in each bacterial species. The human or animal icon on each bar represents the first discovery of estX-carrying bacteria within that host. To reduce false positives, our analysis focused exclusively on bacteria-carrying genes encoding proteins with 100% sequence identity to EstX.
