Table 1 Overview of L5UR/ Raf-RBD in vitro binding data

From: Identification of an H-Ras nanocluster disrupting peptide

Protein

Probe

KDb or IC50/µM

GST-B-RBD

L5UR

7.3 ± 0.7b

GST-B-RBD

L5URa

2 ± 1

GST-B-RBD

L5URcorea

41 ± 1

B-RBD

L5URcore (QRET)

18 ± 1

C-RBD

L5URa

4 ± 1

C-RBD

L5URcorea

14 ± 6

  1. aIn competitive fluorescence polarization assay with F-L5UR.
  2. bMarks actual KD, while otherwise IC50 are reported.
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