Fig. 4: Schematic of the extended anisotropic scrunching model with a baton-pass mechanism. | Communications Biology

Fig. 4: Schematic of the extended anisotropic scrunching model with a baton-pass mechanism.

From: Anisotropic scrunching of SMC with a baton-pass mechanism

Fig. 4

A Ycg1/Brn1 anchors DNA and the hinge captures the DNA baton, which is in a truncated cone area within the anisotropic region. B The DNA segment held by the Ycs4/Brn1 pocket can escape due to the space between the pocket and the neck of SMC2. C When ATP binds to the SMC heads, the heads are dimerized and the arms of the SMC are folded. D The Ycs4/Brn1 DNA pocket is closed, and E the hinge passes the DNA baton to the DNA pocket. F After ATP hydrolysis, the DNA pocket is open to release the DNA baton and the SMC arms are extended.

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