Table 1 Activation of agr in L. monocytogenesa

From: A short-lived peptide signal regulates cell-to-cell communication in Listeria monocytogenes

compound

%-activation [2 μM]

%-activation [80 nM]

P1

11 ± 6b

inactivec,d

P2

160 ± 51b

inactivec,d

P3

15 ± 6b

inactivec,d

1

63 ± 5

35 ± 3

6

27 ± 3

inactivec

7

210 ± 10

38 ± 2

8

270 ± 10

43 ± 8

9

80 ± 5

74 ± 8

10

350 ± 12

274 ± 7

  1. Activation levels surpassing 100% are highlighted in bold.
  2. aValues are extracted from assays with ΔagrD::P2-lux and normalized to average maximum luminescence of untreated ΔagrD::P2-lux (0%) and average maximum luminescence of untreated WT::P2-lux (100%).
  3. bTested at 5 μM.
  4. cInactive defined as less than 10% normalized activation.
  5. dTested at 500 nM.