Table 3 MICs of TM5 and traditional antibiotics against clinical strains of P. aeruginosa
From: Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection
Peptoid/Antibiotic | Sequence | MIC | ||||
|---|---|---|---|---|---|---|
PA14 | PAZK2870 | PAZK2019 | PAZK69 | PAZK3095 | ||
TM5 | H-Ntridec-NLys-Nspe-Nspe-NLys-NH2 | 8 µg/ml | 8 µg/ml | 8 µg/ml | 8 µg/ml | - |
Ciprofloxacin | C17H18FN3O3 | 0.125 µg/ml | 0.125 µg/ml | 0.125 µg/ml | 0.06 µg/ml | 0.25 µg/ml |
Ceftazidime | C22H22N6O7S2 | 2 µg/ml | 2 µg/ml | 2 µg/ml | 1 µg/ml | 1 µg/ml |
Kanamycin | C18H36N4O11 | 32 µg/ml | 64 µg/ml | 64 µg/ml | 32 µg/ml | 64 µg/ml |
Meropenem | C17H25N3O5S | 0.5 µg/ml | 1 µg/ml | 1 µg/ml | 2 µg/ml | 0.5 µg/ml |
