Fig. 2: Comparing the false positive rate (FPR) of starTracer and Seurat on simulated data. | Communications Biology

Fig. 2: Comparing the false positive rate (FPR) of starTracer and Seurat on simulated data.

From: starTracer is an accelerated approach for precise marker gene identification in single-cell RNA-Seq analysis

Fig. 2

A UMAP plot of the simulated data, including five clusters. B False positive rate of starTracer and Seurat in 5 clusters. Blue line indicates the FPR of starTracer’s module “searchMarker”. Yellow line indicates the FPR of Seurat’s “FindAllMarkers”. C The intersection of the top-N markers found by starTracer and Seurat with the ground-truth markers, respectively (blue for starTracer overlap with ground-truth, yellow for Seurat overlap with ground truth) and the intersection of the top-N markers found by starTracer and Seurat (gray). Red dash line (y = x) indicates the ideal situation where the top-N markers completely overlap with the ground-truth markers.

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