Fig. 2: Functional Connectivity fingerprints during AD. | Communications Biology

Fig. 2: Functional Connectivity fingerprints during AD.

From: Fingerprints of brain disease: connectome identifiability in Alzheimer’s disease

Fig. 2

AC Identifiability matrices show within- (ISelf) and between-subjects (IOthers) test–retest reliability as Pearson correlation coefficient in CU Aβ− (Geneva N = 16; ADNI N = 40), MCI Aβ+ (Geneva N = 32; ADNI N = 21) and AD dementia (Geneva N = 6; ADNI N = 11), for the two independent cohorts investigated (Geneva N = 54 and ADNI N = 72, see “Methods” for details). Individuals’ ISelf and IOthers are displayed, respectively, in the diagonal and off-diagonal elements of the matrix. The average ISelf, IDiff and Success-rate were similar in the three groups and IDiff and Success-rate significantly differed from random distributions. BD Boxplots shows that ISelf was significantly higher (paired-sample t-test) than IOthers in all individual cases and in all groups, for both the Geneva and the ADNI datasets. **p ≤ 0.01. Error bars indicate the 25th and 75th percentiles.

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