Fig. 2: Model fitting and validation of the baseline models. | Communications Biology

Fig. 2: Model fitting and validation of the baseline models.

From: Whole brain modelling for simulating pharmacological interventions on patients with disorders of consciousness

Fig. 2

A Model fit curves where the parameter G is optimised to maximise the SSIM to the empirical FC. The optimal values of G for each condition (mean + -std: GUWS = 1.59 + −0.04; GMCS = 1.75 + −0.07; GCNT = 2.1 + −0.06) align with existing literature, where lower G is associated with reduced consciousness. Error bars show standard error for each G value. B The optimal model for each condition exhibits significantly better SSIM values to its corresponding empirical dataset compared to the rest, as shown in the dashed line for each condition.

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