Fig. 4: Comparisons of APKD-induced mice vs control mice.
From: Multiscale and multimodal evaluation of autosomal dominant polycystic kidney disease development
Analysis of Pax8rtTA; TetO-Cre; PKD2fl/fl mice administered oral doxycycline versus untreated, age-matched controls 12 weeks post-doxycycline treatment. A Shows PKD2 expression levels (n = 4–10), B details the kidney-to-body weight ratio (n = 4–10), C presents the cystic index (n = 3), D lists urinary creatinine (n = 4–6) and E outlines serum urea nitrogen levels (n = 4–10). Mean values were evaluated for statistically significant differences with the use of a two-factor ANOVA, and all pairwise comparisons were run with a Bonferroni adjustment. Data are expressed as mean values ± SEM. DOX denotes doxycycline.
