Fig. 4: Dynamic states in resting-state fMRI from different populations.
From: Identifying individual brain development using multimodality brain network
a The dynamic functional connectivity states averaged from healthy individuals with ages older than 18 years (n = 10). Left, the heat maps show the connectivity scores of paired brain regions in the three states. Right, the box-plots show the probability (blue) and variability (red) of the three states, which calculated between the ages of 5 and 21 in each population (nHealthy = 203, nAD = 113, nDD = 57, nADHD = 406, nASD = 66, nCELF = 298, nLD = 73). The two-sample t tests (two-sided) were conducted between the healthy population and the other six populations, respectively. Boxes represent interquartile range (IQR), central lines indicate the median, whiskers indicate 1.5 × IQR, notches indicate median ± (1.57 × IQR)/sqrt(n) and dot symbols indicate outliers. (b) The correlation between the parameters (probability and variability) of the three dynamic states and the age in seven populations. Dot colors represent r-values and dot sizes represent p-values. AD: anxiety disorder; DD: depression disorder; ADHD: attention deficit hyperactivity disorder; ASD: autism spectrum disorder; CELF: below clinical evaluation of language fundamentals criterion; LD: learning disorder. *p < 0.05, **p < 0.01 and ***p < 0.001.
