Fig. 6: The conceptual model for FA crosslinking and insights into the selection of optimal conditions. | Communications Biology

Fig. 6: The conceptual model for FA crosslinking and insights into the selection of optimal conditions.

From: Crosslinking intensity modulates the reliability and sensitivity of chromatin conformation detection at different structural levels

Fig. 6

a A schematic diagram of the model, where \(\sigma\) represents the standard deviation that regulates the strength of crosslinking. b The mean contact frequency decay curves as functions of central distance \(D\) under varying crosslinking strengths, based on 500 simulation runs. c The coefficient of variance values, which indicate the signal-to-noise ratio, as functions of central distance \(D\) under different crosslinking strengths, calculated from the 500 simulation runs.

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