Fig. 5: GRIN enhances gene set enrichment analysis.
From: Analyses of GWAS signal using GRIN identify additional genes contributing to suicidal behavior
Using genes intersecting in two or more GWAS summary statistics (shaded blue region of Venn diagram) prior to GRIN resulted in 1324 enrichments. Intersecting genes retained by GRIN (28 genes) resulted in 1443 enrichments, 1268 of which were common prior to GRIN. Green: Enrichments using intersecting genes prior to GRIN; yellow: enrichments using intersecting genes from GRIN retained genes; purple: enrichments common to unfiltered and GRIN-retained genes.
