Fig. 5: VapBC13 and VapBC26 are required for the survival of M. tuberculosis during oxidative stress conditions. | Communications Biology

Fig. 5: VapBC13 and VapBC26 are required for the survival of M. tuberculosis during oxidative stress conditions.

From: Deciphering the role of VapBC13 and VapBC26 toxin antitoxin systems in the pathophysiology of Mycobacterium tuberculosis

Fig. 5

The transcript levels of vapB13 (A) and vapB26 (D) were measured in ΔvapC13 and ΔvapC26 strains, respectively, by quantitative real-time PCR using gene-specific primers. The data obtained was normalized to sigA and is shown as the mean ± SD of fold change obtained from three independent experiments. B, C, E, F The bacterial loads of various strains were determined after exposure to 5 mM H2O2 for either 24 h or 72 h. The data shown in these panels is the mean ± SD of data obtained from two independent experiments performed in duplicates. P values depicted on the graphs were assessed using one-way ANOVA. Source data is provided in Supplementary Data Set 4.

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