Fig. 1: Construction of key functional gene analysis platform. | Communications Biology

Fig. 1: Construction of key functional gene analysis platform.

From: Regulating the metabolic flux of pyruvate dehydrogenase bypass to enhance lipid production in Saccharomyces cerevisiae

Fig. 1

Based on population data, biological information involving multiple genes and traits can be obtained with high throughput. The phenome, genome, transcriptome, and metabolome combination strategy were used to further target key functional genes, and the metabolic pathways in which the genes reside and specific biological function changes were understood in detail. Finally, the function of key genes was verified using gene knockout or overexpression, which confirmed that the candidate genes that were mined truly regulated the target phenotype. (Some icons created in BioRender).

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