Fig. 1: Pedigrees of the 13 multi-child IRASFS families. | Communications Biology

Fig. 1: Pedigrees of the 13 multi-child IRASFS families.

From: Mutational signature analyses in multi-child families reveal sources of age-related increases in human germline mutations

Fig. 1

Each IRASFS Family is labeled with a sequential number 1–13. Within each family, fathers and mothers are identified with the numbers 1 and 2, respectively, while each child is identified by the letter p (proband) and a number representing the order of birth. The number under each child represents the paternal age at the time of birth for that child. The youngest and oldest paternal ages in this IRASFS cohort are 16.4 years old (IRASFS Family 9 - proband #1) and 41.2 years old (IRASFS Family 10 -proband #5), respectively. Gray circles indicate the individuals that were sequenced for this study. All other whole-genome sequences were already available from IRASFS.

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