Fig. 4: The parent of origin of de novo SNVs in the IRASFS families. | Communications Biology

Fig. 4: The parent of origin of de novo SNVs in the IRASFS families.

From: Mutational signature analyses in multi-child families reveal sources of age-related increases in human germline mutations

Fig. 4

A Box plots representing the proportion of validated de novo SNVs that were successfully phased to establish the parent of origin. B Scatter plot with fitted regression line ± 95% confidence interval of the distribution of phased de novo SNVs in each of the 48 children based on the paternal age at the time of birth. Maternally-based SNVs are plotted according to the age of the father at the time of child’s birth because maternal age was not available.

Back to article page