Fig. 2: Manhattan plot of genome-wide association studies for serum uric acid and total cholesterol levels. | Communications Biology

Fig. 2: Manhattan plot of genome-wide association studies for serum uric acid and total cholesterol levels.

From: Population-specific reference panel improves imputation quality for genome-wide association studies conducted on the Japanese population

Fig. 2

Manhattan plot of genome-wide association with (a) serum uric acid levels and (b) total cholesterol levels, conducted using 104,174 and 122,407 Japanese individuals from the Biobank Japan Project respectively. Each point represents a variant passing quality control (r2 > 0.3 and MAF > 0.1%), plotted with their association p-value (on a -log10 scale) as a function of genomic position (NCBI build 37). Association signals attaining genome-wide significance (p < 5 × 10–8), indicated by grey horizontal line, and significant associations unique to 1KG+7K are highlighted in red.

Back to article page