Fig. 6: Causal inference of AD-GID associations using bi-directional MR analysis.
From: An atlas of the shared genetic architecture between atopic and gastrointestinal diseases
A Schematic workflow of MR analysis (Methods), including IVs selection and quality controls, primary and complementary MR approaches, and sensitivity analysis. B A total of five unidirectional causal relationships with FDRIVW < 0.05 were identified, and one significant bi-directional causality between GERD and asthma (both directional FDRIVW < 0.05). All results shown passed quality control and sensitivity analysis. NS, non-significant.
