Fig. 4: Integrated scRNA-seq and bulk RNA-seq analysis revealed that microglial SMEK1 deficiency suppresses mitochondrial oxidative phosphorylation.

A Dot plots of microglia-related genes expressed among cell clusters. B Volcano map of marker genes in different microglial clusters. C Dot plots showing differences in metabolic characteristics between SMEK1−/− and wild-type mice. D Dot plots showing metabolic characteristics of seven microglial clusters between SMEK1−/− and wild-type mice.