Table 1 Effects of diet and tumor growth on serum lipid parameters in mice

	CR	CR tumor-bearing	Chow	Chow tumor-bearing	HFHS	HFHS tumor-bearing
Total triglycerides	0.48 ± 0.09	0.28 ± 0.03^a	0.39 ± 0.05	0.79 ± 0.12^b	0.69 ± 0.03^a	0.92 ± 0.11^c,d
Total CHOL	0.64 ± 0.04	0.52 ± 0.03	0.61 ± 0.03	0.75 ± 0.05^b,c	0.87 ± 0.03^a	0.96 ± 0.07^c,e
Total HDL	0.21 ± 0.03	0.20 ± 0.02	0.15 ± 0.02	0.20 ± 0.02	0.28 ± 0.02^b	0.21 ± 0.02^e
Total LDL	6.78 ± 0.60	8.07 ± 0.38^a	7.88 ± 0.45	11.01 ± 1.27^b	8.36 ± 0.86^a,b	23.11 ± 2.63^c,d,e

Serum lipid profile in all tumor-free or tumor-bearing mice from CR, Chow, and HFHS groups. Serum parameters are in μg/μL. All plotted values are mean ± S.E.M. of four to five animals. For statistics, two-way ANOVA followed by Tukey’s post-test was used and P < 0.05 was considered statistically significant.
Serum parameters are in μg/μL. Data are presented as means ± SEM (n = 4–5).
CHOL cholesterol, LDL low-density lipoprotein, HDL high-density lipoprotein.
^aSignificantly different compared to CR.
^bSignificantly different compared to Chow.
^cSignificantly different compared to CR tumor-bearing.
^dSignificantly different compared to HFHS.
^eSignificantly different compared to Chow tumor-bearing.

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