Fig. 1: Presented workflow for generation of 3D synthetic images featuring nuclei and membrane signals.
From: Improving 3D deep learning segmentation with biophysically motivated cell synthesis
3D cell cultures are imaged using confocal microscopy. Afterward, parameters are extracted based on the recorded images, which are then utilized during cell simulation to generate synthetic cell border images. Finally, synthetic nuclei and membrane images are generated on the basis of the simulated cell border image.
