Table 1 Maternal and neonatal characteristics, and delayed myelination in term-equivalent age-MRI between the non-HCA and HCA groups
| Â | non-HCA | HCA | p-value |
|---|---|---|---|
|  | (n = 78) | (n = 16) | |
Maternal characteristics | Â | Â | Â |
 Maternal age (years) | 35 [26–42] | 37 [25–43] | 0.18 |
 Primiparous | 41 (52.6%) | 6 (37.5%) | 0.41a |
 Gestational age at delivery (weeks) | 30.8 [24.0–34.0] | 31.1 [24.4–33.7] | 0.33 |
 Cesarean section | 70 (89.7%) | 14 (87.5%) | 0.68 |
 Antenatal corticosteroid treatment | 49 (62.8%) | 11 (68.8%) | 0.78a |
 Antenatal magnesium sulfate treatment | 26 (33.3%) | 5 (31.2%) | >0.99 |
Neonatal characteristics | Â | Â | Â |
 Male | 44 (58.7%) | 8 (50.0%) | 0.59a |
 Birth weight (g) | 1303 [506–2482] | 1358 [624–2294] | 0.69 |
 Birth weight (z-score) | −0.60 [−4.10–3.10] | −0.20 [−1.50–1.20] | 0.048 |
 Small for gestational age | 29 (37.2%) | 1 (6.2%) | 0.02 |
 Respiratory distress syndrome | 40 (51.3%) | 7 (43.8%) | 0.79a |
 Duration of intubation (days) | 1 [0–79] | 2 [0–67] | 0.94 |
 Bronchopulmonary dysplasia | 17 (21.8%) | 4 (25.0%) | 0.75 |
 Intraventricular hemorrhage (grade 1 or 2) | 2 (2.6%) | 2 (12.5%) | 0.13 |
 Patent ductus arteriosus ligation | 1 (1.3%) | 0 (0.0%) | >0.99 |
 Inotrope use | 5 (6.7%) | 3 (18.8%) | 0.14 |
 Postnatal steroid use | 5 (6.7%) | 1 (6.2%) | >0.99 |
 Necrotizing enterocolitis | 0 (0.0%) | 0 (0.0%) | ND |
 Infection | 3 (3.8%) | 5 (31.2%) | 0.003 |
 Treated retinopathy of prematurity | 7 (9.0%) | 2 (12.5%) | 0.65 |
 Duration of hospitalization (days) | 66 [29–141] | 66 [28–156] | 0.91 |
MRI at term-equivalent age | Â | Â | Â |
 Delayed myelination | 4 (5.1%) | 4 (25.0%) | 0.03 |
