Fig. 2: Intracranial recordings provide neural measurements with high resolution and broad anatomical coverage.
From: Human response times are governed by dual anticipatory processes with distinct neural signatures
A Extracting high-frequency activity (HFA, 70–200 Hz power) from intraparenchymal depth electrodes as an estimate of local spiking (red circle indicates example prefrontal electrode described in C). B Brain plot showing electrode locations from all participants in standard MNI coordinates. Colors indicate intrinsic brain networks based on a normative atlas (Yeo et al., 2011). C Task-driven responses of local neural activity (average z-scored HFA) measured at the electrode indicated in (A), plotted separately for short- (left panel, blue) and long- (right panel, orange) delay trials and binned by RT tertiles (3 bins, computed within each participant; lighter shading indicates faster RTs). Main panels shows target-locked activity. Vertical lines indicate time of target onset (gray), short-delay color change (blue), and long-delay color change (orange). Insets on top right show response-locked activity. Shaded gray box indicates the time interval during which we observed a correlation between neural activity and RT variability.
