Fig. 6: Effects of formulated bambuterol in mice in the Morris water maze. | Communications Biology

Fig. 6: Effects of formulated bambuterol in mice in the Morris water maze.

From: Evidence from a mouse model supports repurposing an anti-asthmatic drug, bambuterol, against Alzheimer’s disease by administration through an intranasal route

Fig. 6

Effects of formulated bambuterol on the total distance swum in the Morris water maze (B), on swim velocity (C), time spent around the supposed location of the platform (ring area) during the retention phase (D) and the latency to reach the ring area (E) [control (white), bambuterol (green)]. No difference was found in learning phase between groups (A) [control (solid-black circles), Aβ1-42 (solid-red squares), Aβ1-42 + bambuterol (solid-green triangles)]. Results are expressed as mean ± SEM [n = 12 except for (A): control (n = 11) and (C): bambuterol (n = 11)]. One-way ANOVA followed by Fisher’s LSD test. *p < 0.05 vs. Aβ1-42 was considered significant (red).

Back to article page