Table 1 EC50 values for the FRET sensor, arrestin interaction, and Go activation from Fig. 2

From: Dynamics of agonist-evoked opioid receptor activation revealed by FRET- and BRET-based opioid receptor conformation sensors

EC50 values

FRET sensor

arrestin3 interaction

Go activation

DAMGO

430 nM

282 nM

2.92 nM

Morphine

6.93 µM

713 µM

29.7 nM

Fentanyl

400 nM

221 nM

1.76 nM

Methadone

1.23 µM

339 nM

2.61 nM

Met-enkephalin

6.83 nM

248 nM

524 pM

Buprenorphine

1.90 µM

n/a

9.72 nM

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