Fig. 1: Genome organization and quality control in CRC samples. | Communications Biology

Fig. 1: Genome organization and quality control in CRC samples.

From: 3D genome landscape of primary and metastatic colorectal carcinoma reveals the regulatory mechanism of tumorigenic and metastatic gene expression

Fig. 1

a Experimental design and data analysis workflow of this study. b Hematoxylin-eosin staining of matched normal colorectum, primary tumor, and liver metastatic tumor from six patients with a scale bar of 50 μm. c PCA of RNA-seq data in normal colon, colorectal tumor, liver metastasis, lymph node metastasis, and normal liver samples. N: normal colorectum, T: primary tumor, M: liver metastasis, LNM: lymph node metastasis, NL: normal liver. d PCA1 snapshot of Hi-C data.

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