Fig. 4: TT in immunocompetent mice exhibit a microenvironment similar to that in humans.
From: New mouse models for exploring renal tumor extension into the inferior vena cava
A Representative mIHC staining figures of CD68 and CD163 in human tissue sections and immunofluorescence staining figures of F4/80 in BALB/c mouse tissue sections. B Representative immunohistochemistry staining figures of CD15 in human tissue sections and Ly6G in BALB/c mouse tissue sections. C Representative IHC staining figures of CD11c in human tissue sections and in BALB/c mouse tissue sections. Data are represented as mean ± SD (n = 3, Unpaired t test with Welch’s correction, *p < 0.05, ns = no significance). ART = adjacent renal tissues; PT = primary tumor; TT = tumor thrombus; scale bars, 50 µm.
