Fig. 6: Single-cell transcriptome sequencing identifies the differences in the composition of tumor thrombus cells between the two groups.
From: New mouse models for exploring renal tumor extension into the inferior vena cava
A UMAP plot depicting the distribution of cells for Renca BALB/c and Renca BALB/c-nu/nu mice. B UMAP showing different cell subsets for Renca BALB/c and Renca BALB/c-nu/nu mice. C Expression of marker genes in different cell subsets. D Pie charts indicating the cell composition for Renca BALB/c mice (left) and Renca BALB/c-nu/nu mice (right). E Bar charts representing the proportion difference of different cell types between Renca BALB/c mice and Renca BALB/c-nu/nu mice. F Monocle pseudotime trajectory showing the progression of renal cells, epithelial–mesenchymal transition (EMT) cells, and fibroblasts. G Using monocytes and macrophages as reference, inferCNV was used to analyze the copy number variation in renal cells, EMT cells, and fibroblasts. In the figure, the horizontal axis is the mean of the meanSquare of each cluster, and the vertical axis is the correlation coefficient.
