Fig. 2: Whole exome genome-wide single-variant tests for cerebellum-related traits.
From: Exome sequencing identifies novel genes associated with cerebellar volume and microstructure
The Manhattan plot displays the results of single-variant tests associated with cerebellum-related traits, including total cerebellar volume, SCP-FA, SCP-MD, MCP-FA, MCP-MD, ICP-FA and ICP-MD. The x-axis represents the position of single variants across the 22 chromosomes, while the y-axis indicates the −log10 P-values for each association. The grey dashed line denotes the significance threshold (P < 1 × 10−8). Variants significantly associated with cerebellum-related traits are labelled with their corresponding genes, with red indicating newly identified genes.
