Fig. 5: Biological functions of genes associated with cerebellum-related traits.
From: Exome sequencing identifies novel genes associated with cerebellar volume and microstructure
a Enrichment analysis of 60 significant genes identified in single-variant and gene-level tests using the GO database. GO_BP refers to GO terms from the biological process domain, GO_CC refers to GO terms from the cellular component domain, and GO_MF refers to GO terms from the molecular function domain. b Enrichment analysis of 68 genes across 54 tissues using FUMA in GTEx. The top 29 tissues are shown in the figure. c Relative expression of cerebellum-associated genes in adult cerebellum single-cell data. Uniform manifold approximation and projection was used to visualise the scRNA-seq data. The colour of each point represents the cell type. d Feature plot showing the expression levels of CAMTA1 across different cell types. e Feature plot showing the expression levels of CARNS1 across different cell types.
