Fig. 4: Comparative CD8 T cell responses in WT mice infected with CoV-OVA or IAV-OVA. | Communications Biology

Fig. 4: Comparative CD8 T cell responses in WT mice infected with CoV-OVA or IAV-OVA.

From: Effector CD8 T cell differentiation in primary and breakthrough SARS-CoV-2 infection in mice

Fig. 4

WT C57BL/6 mice were infected with 1000 PFU of CoV-OVA or 500 PFU of IAV-OVA. On days 8 and 10 post-infection, mice were euthanized, and lungs were collected for CD8 T cell analysis. A FACS plots and graphs show frequencies of SIINFEKL-specific CD8 T cells in the lungs. B Graphs show frequencies of CD69 + CD103+, KLRG1 + CX3CR1+, CD127+, PD-1+, and TIGIT+ or C frequencies granzyme B+, and STAT-3+ among SIINFEKL-specific CD8 T cells. Data represent two independent experiments. Data in each graph indicate mean ± SEM.

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