Fig. 1: The expression of Piezo1 in human preterm infants and neonatal mice. | Communications Biology

Fig. 1: The expression of Piezo1 in human preterm infants and neonatal mice.

From: Piezo1 promotes the progression of necrotizing enterocolitis by activating the Ca2(+)/CaMKII-dependent pathway

Fig. 1

A Representative images of IHC analysis of Piezo1 expression in neonates with different GA (Scale bar: 100 μm). B qRT-PCR showing the expression of Piezo1 in neonates with different GA (n = 5 biologically independent samples). C Representative images of Piezo1 immuno-stained sections of human and mouse intestinal specimens from control and NEC patients or animals (Scale bar: 100 μm). D Expression of Piezo1 by qRT-PCR in the small intestine of mouse (n = 6 mice) and human (n = 7 biologically independent samples). E Representative images of IHC analysis of Piezo1 expression in the intestine of mice during the postnatal period at the indicated times. F qRT-PCR showing the expression relative to GAPDH of Piezo1 in the intestine of mice during the postnatal period at the indicated times (n = 8,12,9,6,6,6 mice). P values were determined by unpaired two-tailed Student’s t test and Mann–Whitney U test, *P < 0.05; **P < 0.01; ***P < 0.001. Data are mean ± SEM.

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