Fig. 4: Improvement of diabetic corneal wound healing with chemical sympathectomy. | Communications Biology

Fig. 4: Improvement of diabetic corneal wound healing with chemical sympathectomy.

From: Norepinephrine regulates epithelial-derived neurotrophins expression and sensory nerve regeneration through ADRB2 receptor

Fig. 4

DM mice were intraperitoneally injected with 6-OHDA and subsequently debrided the central corneal epithelium. A, B Mouse plasma and corneal NE concentrations were measured with ELISA kits at 12 h and 24 h post wounding (n = 3 mice per group). C Mouse corneal epithelial wound healing was monitored with fluorescein staining. D Corneal epithelial defects were calculated with Image J software (n = 5 mice per group). Data are representative of the mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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