Fig. 7: Inhibition of rhVEGF-induced HUVEC proliferation by ORN 3 and ORN 4 G4s.

a Anti-proliferation effect of ORN 3 and ORN 4 G4s on HUVECs stimulated by VEGF (n = 3). b Wound healing assay analyzed the effects of ORN 3 and ORN 4 G4s on HUVECs migration stimulated by VEGF. Scale bar: 250 μm (n = 3). c Transwell assay analyzed the effects of ORN 3 and ORN 4 G4s on HUVECs migration stimulated by VEGF. Scale bar: 250 μm. **P < 0.01 vs. control group; ##P < 0.01 vs. VEGF group (Student’s t-test) (n = 3).