Fig. 2: Overexpression of PTOV1 facilitates tumor cell growth.
From: PTOV1 interacts with ZNF449 to promote colorectal cancer development
A Cell growth curves measured by CCK-8 between Vector and oePTOV1. B PTOV1 overexpression facilitated colony formation and histogram quantification (panels). C Transwell assays showing that overexpression of PTOV1 facilitates cell migration and invasion. The numbers of migration and invading cells are shown. Bars: 50 μm. D Typical pictures of subcutaneous tumor between Vector and oePTOV1. Representative pictures of Ki-67 staining between Vector and oePTOV1. Bars: 50 um. The means ± SDs are provided (n = 3). *P < 0.05, **P < 0.01, and ***P < 0.001 according to two-tailed Student t-tests or one-way ANOVA followed by Dunnett tests for multiple comparisons.
